GFI1B

Across TCGA cell cohorts, GFI1B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GFI1B-associated genes across cancer lineages are HTR1B, CPLX4, and MAGEB10. Each is linked with GFI1B in more than 1 cancer types. Because this analysis shows association rather than direction, both GFI1B-to-partner and partner-to-GFI1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HTR1B grouped by GFI1B-low versus GFI1B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFI1B→partner) and Y-score (partner→GFI1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HTR1B →	+0.077	+4.029	<.001	.004	3	1
LARGE_INTESTINE	CPLX4 →	+0.027	+4.392	.001	.004	3	1
LARGE_INTESTINE	MAGEB10 →	+0.087	+3.930	<.001	.003	3	1
LUNG_NSCLC_LUAD	CCL18 →	+0.050	+4.212	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

HTR1B by GFI1B expression — LARGE_INTESTINE

Explore this box plot interactively →