GFI1

Across TCGA patient cohorts, GFI1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,713 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GFI1-associated proteins across cancer lineages are PSMB10, RASAL3, and APOL3. Each is linked with GFI1 in more than 9 cancer types. Because this analysis shows association rather than direction, both GFI1-to-partner and partner-to-GFI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFI1 versus PSMB10 in GBM, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GFI1→partner) and Y-score (partner→GFI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PSMB10 →	+0.667	+0.535	<.001	<.001	3	10
LSCC	RASAL3 →	+0.474	+0.825	<.001	<.001	3	10
UCEC	APOL3 →	+0.784	+0.681	<.001	<.001	3	10
BRCA	ARHGAP15_S64 →	+0.903	+0.706	<.001	<.001	3	10
OV	ARHGAP25 →	+1.338	+0.962	.005	<.001	3	10
UCEC	ARHGAP30 →	+0.654	+0.710	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,713 associations by consensus.

GFI1 vs PSMB10 — GBM

Explore this scatter interactively →