GFAP

Across TCGA patient cohorts, GFAP RNA expression is significantly associated with the protein abundance of many other proteins, with 7,365 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GFAP-associated proteins across cancer lineages are ARHGEF17, EIF3L, and PSME4. Each is linked with GFAP in more than 3 cancer types. Because this analysis shows association rather than direction, both GFAP-to-partner and partner-to-GFAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GFAP versus ARHGEF17 in COAD, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GFAP→partner) and Y-score (partner→GFAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ARHGEF17 →	+0.510	+0.115	<.001	<.001	3	4
BRCA	EIF3L →	-0.219	-0.194	<.001	.001	3	4
BRCA	PSME4 →	-0.282	-0.146	.001	.002	3	3
BRCA	PTGR1 →	+0.489	+0.197	<.001	<.001	3	3
GBM	PYGM →	+0.657	+0.723	.001	.002	3	3
BRCA	RCL1 →	-0.286	-0.176	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,365 associations by consensus.

GFAP vs ARHGEF17 — COAD

Explore this scatter interactively →