GFAP

Across TCGA patient cohorts, GFAP mutation is significantly associated with the RNA expression of many other genes, with 1,006 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GFAP-associated genes across cancer lineages are RN7SKP117, MIR5680, and NCAPH2. Each is linked with GFAP in more than 2 cancer types. Because this analysis shows association rather than direction, both GFAP-to-partner and partner-to-GFAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP117 grouped by GFAP-low versus GFAP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GFAP→partner) and Y-score (partner→GFAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SKP117 →	+0.133	+3.394	<.001	.001	3	3
LGG	MIR5680 →	+0.564	+5.392	<.001	.005	3	2
UCEC	NCAPH2 →	+0.664	+4.247	<.001	<.001	3	2
UCEC	HIRA →	+0.425	+2.021	.004	.005	3	2
UCEC	SNU13 →	+0.289	+3.418	.008	.004	3	2
UCEC	RTCB →	+0.485	+2.639	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,006 associations by consensus.

RN7SKP117 by GFAP expression — SKCM

Explore this box plot interactively →