GFAP

Across TCGA cell cohorts, GFAP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,102 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GFAP-associated GO terms across cancer lineages are Cytoplasmic translation, Regulation of intracellular transport, and Vesicle-mediated transport to the plasma membrane. Each is linked with GFAP in more than 9 cancer types. Because this analysis shows association rather than direction, both GFAP-to-partner and partner-to-GFAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by GFAP-low versus GFAP-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GFAP→partner) and Y-score (partner→GFAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Cytoplasmic translation →	+0.082	+0.378	<.001	<.001	3	10
OVARY	Regulation of intracellular transport →	+0.044	+0.299	<.001	.006	3	10
BREAST	Vesicle-mediated transport to the plasma membrane →	+0.071	+0.416	<.001	<.001	3	9
BONE	Regulation of cell-substrate junction organization →	+0.157	+0.435	.004	.006	3	9
BREAST	Oxidative phosphorylation →	+0.092	+0.427	<.001	<.001	2	10
BREAST	Respiratory electron transport chain →	+0.076	+0.381	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,102 associations by consensus.

Cytoplasmic translation by GFAP expression — BREAST

Explore this box plot interactively →