GET4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GET4 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,405 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GET4-associated proteins across cancer lineages are ATAD3A, SPCS3, and AVL9. Each is linked with GET4 in more than 2 cancer types. Because this analysis shows association rather than direction, both GET4-to-partner and partner-to-GET4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GET4 versus ATAD3A in LSCC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GET4→partner) and Y-score (partner→GET4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCATAD3A →+0.330+0.214<.001<.00133
LSCCSPCS3 →-0.606-0.198<.001<.00133
LUADAVL9 →+0.253+0.174<.001<.00133
LUADCHCHD2 →+0.336+0.315<.001<.00133
LSCCCRELD2 →-0.499-0.188<.001<.00133
LSCCDDX56 →+0.303+0.163<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,405 associations by consensus.

GET4 vs ATAD3A — LSCC

Per-sample scatter of GET4 vs ATAD3A in LSCC (Pearson r = 0.37).

Explore this scatter interactively →

Exploration