GET4

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GET4 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GET4-associated genes across cancer lineages are Monocytes and Skeletal muscle. Each is linked with GET4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GET4-to-partner and partner-to-GET4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by GET4-low versus GET4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GET4→partner) and Y-score (partner→GET4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMonocytes →+0.072+6.734<.001.01831
SKCMSkeletal muscle →+0.052+2.813.023.03731
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Monocytes by GET4 expression — COAD

Box plot of Monocytes in GET4-low vs GET4-high samples in COAD.

Explore this box plot interactively →

Exploration