Across TCGA pan-cancer cohorts, GET3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GET3 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GET3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GET3 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and GBM show a favorable association.

UCEC, CCRCC, and HNSC are the cancer types where GET3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Tertile	All	0.821	1.000	.004	18	view →
CCRCC	DFS	Median	All	0.878	0.743	.018	5	view →
HNSC	OS	Quartile	II,III,IV	0.570	0.836	.022	4	view →
GBM	OS	Quartile	All	0.711	0.407	.037	1	view →
PDAC	OS	Median	III,IV	0.516	0.873	.037	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: GET3 tumor-vs-normal RNA expression · all GET3 data types