GET1

Across TCGA patient cohorts, GET1 mutation is significantly associated with the RNA expression of many other genes, with 352 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GET1-associated genes across cancer lineages are BMS1P9, DEFB103A, and RN7SL640P. Each is linked with GET1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GET1-to-partner and partner-to-GET1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMS1P9 grouped by GET1-low versus GET1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GET1→partner) and Y-score (partner→GET1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BMS1P9 →	+0.142	+2.285	.001	.006	3	2
LUAD	DEFB103A →	+0.059	+7.930	<.001	.008	3	1
LUSC	RN7SL640P →	+0.119	+7.924	<.001	.008	3	1
SKCM	FTH1P9 →	+0.104	+7.228	<.001	<.001	3	1
SKCM	RNU6-1174P →	+0.295	+4.771	<.001	.006	3	1
SKCM	SLC2A13P1 →	+0.162	+5.328	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 352 associations by consensus.

BMS1P9 by GET1 expression — UCEC

Explore this box plot interactively →