GET1

Across TCGA cell cohorts, GET1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,015 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GET1-associated GO terms across cancer lineages are Regulation of smoothened signaling pathway, Positive regulation of organelle assembly, and Protein localization to cilium. Each is linked with GET1 in more than 10 cancer types. Because this analysis shows association rather than direction, both GET1-to-partner and partner-to-GET1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of smoothened signaling pathway grouped by GET1-low versus GET1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GET1→partner) and Y-score (partner→GET1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of smoothened signaling pathway →	+0.036	+0.764	<.001	.003	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of organelle assembly →	+0.059	+0.883	.002	.001	3	9
BREAST	Protein localization to cilium →	+0.052	+0.758	<.001	<.001	3	9
BREAST	DNA synthesis involved in DNA repair →	+0.092	+1.123	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Tail-anchored membrane protein insertion into ER membrane →	+0.097	+0.865	<.001	<.001	3	9
OVARY	Defense response to bacterium →	-0.095	-0.491	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,015 associations by consensus.

Regulation of smoothened signaling pathway by GET1 expression — BLOOD_Lymphoma

Explore this box plot interactively →