GEMIN8

Across TCGA patient cohorts, GEMIN8 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,617 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GEMIN8-associated proteins across cancer lineages are CTPS2, WAS, and FERMT3. Each is linked with GEMIN8 in more than 7 cancer types. Because this analysis shows association rather than direction, both GEMIN8-to-partner and partner-to-GEMIN8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GEMIN8 versus CTPS2 in COAD, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN8→partner) and Y-score (partner→GEMIN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CTPS2 →	+0.389	+0.490	.002	<.001	3	8
GBM	WAS →	-0.492	-0.300	<.001	<.001	3	6
GBM	FERMT3 →	-0.507	-0.412	.005	.002	3	6
GBM	LCP1 →	-0.577	-0.289	<.001	.001	3	6
GBM	ARHGAP30 →	-0.477	-0.307	<.001	<.001	3	5
GBM	ARHGAP45 →	-0.531	-0.350	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,617 associations by consensus.

GEMIN8 vs CTPS2 — COAD

Explore this scatter interactively →