GEMIN8

Across TCGA cell cohorts, GEMIN8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,345 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GEMIN8-associated GO terms across cancer lineages are Intraciliary anterograde transport, Cilium-dependent cell motility, and Cilium movement involved in cell motility. Each is linked with GEMIN8 in more than 9 cancer types. Because this analysis shows association rather than direction, both GEMIN8-to-partner and partner-to-GEMIN8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary anterograde transport grouped by GEMIN8-low versus GEMIN8-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN8→partner) and Y-score (partner→GEMIN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Intraciliary anterograde transport →	+0.100	+1.198	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.130	-0.952	<.001	.001	2	10
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.111	-0.746	<.001	.004	2	10
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.130	-0.952	<.001	.001	2	10
CNS	Protein localization to ciliary transition zone →	+0.068	+0.709	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.120	-0.859	<.001	.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,345 associations by consensus.

Intraciliary anterograde transport by GEMIN8 expression — BREAST

Explore this box plot interactively →