GEMIN8

Across TCGA cell cohorts, GEMIN8 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GEMIN8-associated genes across cancer lineages are TEX26, IFNA4, and ARMS2. Each is linked with GEMIN8 in more than 1 cancer types. Because this analysis shows association rather than direction, both GEMIN8-to-partner and partner-to-GEMIN8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TEX26 grouped by GEMIN8-low versus GEMIN8-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN8→partner) and Y-score (partner→GEMIN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TEX26 →	+0.035	+5.539	<.001	.003	3	1
BLOOD_Leukemia	IFNA4 →	+0.055	+4.922	<.001	.009	3	1
BLOOD_Leukemia	ARMS2 →	+0.021	+4.922	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TEX26 by GEMIN8 expression — BLOOD_Leukemia

Explore this box plot interactively →