GEMIN6

Across TCGA patient cohorts, GEMIN6 protein abundance is significantly associated with the RNA expression of many other genes, with 6,583 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GEMIN6-associated genes across cancer lineages are FLI1, CCDC141, and IL16. Each is linked with GEMIN6 in more than 3 cancer types. Because this analysis shows association rather than direction, both GEMIN6-to-partner and partner-to-GEMIN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GEMIN6 versus FLI1 in LSCC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN6→partner) and Y-score (partner→GEMIN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FLI1 →	-0.546	-0.184	<.001	.004	3	4
HNSC	CCDC141 →	-0.760	-0.267	.001	<.001	3	4
HNSC	IL16 →	-0.601	-0.224	.001	.001	3	4
HNSC	PODN →	-0.925	-0.251	.001	.001	3	4
LSCC	PNO1 →	+0.517	+0.248	<.001	<.001	3	3
UCEC	SNED1 →	-0.591	-0.231	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,583 associations by consensus.

GEMIN6 vs FLI1 — LSCC

Explore this scatter interactively →