GEMIN5

Across TCGA patient cohorts, GEMIN5 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,648 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GEMIN5-associated proteins across cancer lineages are MCM2, MCM4, and MCM6. Each is linked with GEMIN5 in more than 6 cancer types. Because this analysis shows association rather than direction, both GEMIN5-to-partner and partner-to-GEMIN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GEMIN5 versus MCM2 in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN5→partner) and Y-score (partner→GEMIN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MCM2 →	+0.497	+0.442	<.001	<.001	3	7
GBM	MCM4 →	+0.543	+0.230	.003	.003	3	7
GBM	MCM6 →	+0.739	+0.251	.002	.009	3	7
LSCC	CMSS1 →	+0.435	+0.377	<.001	<.001	3	6
PDAC	CSE1L →	+0.343	+0.389	<.001	<.001	3	6
GBM	RFC2 →	+0.440	+0.337	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,648 associations by consensus.

GEMIN5 vs MCM2 — LSCC

Explore this scatter interactively →