GEMIN5

Across TCGA patient cohorts, GEMIN5 protein abundance is significantly associated with the RNA expression of many other genes, with 15,022 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GEMIN5-associated genes across cancer lineages are CENPH, PTTG1, and KIF20A. Each is linked with GEMIN5 in more than 9 cancer types. Because this analysis shows association rather than direction, both GEMIN5-to-partner and partner-to-GEMIN5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GEMIN5 versus CENPH in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN5→partner) and Y-score (partner→GEMIN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CENPH →	+0.810	+0.276	<.001	<.001	3	10
UCEC	PTTG1 →	+1.401	+0.326	<.001	<.001	3	10
HNSC	KIF20A →	+1.295	+0.249	<.001	<.001	3	9
BRCA	CSE1L →	+0.777	+0.284	<.001	<.001	3	9
UCEC	CCNB1 →	+0.982	+0.176	<.001	<.001	3	9
UCEC	CDC25C →	+1.033	+0.218	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,022 associations by consensus.

GEMIN5 vs CENPH — HNSC

Explore this scatter interactively →