GEMIN5

Across TCGA cell cohorts, GEMIN5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,353 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GEMIN5-associated GO terms across cancer lineages are Maturation of 5.8S rRNA, DNA replication initiation, and rRNA 5'-end processing. Each is linked with GEMIN5 in more than 18 cancer types. Because this analysis shows association rather than direction, both GEMIN5-to-partner and partner-to-GEMIN5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of 5.8S rRNA grouped by GEMIN5-low versus GEMIN5-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN5→partner) and Y-score (partner→GEMIN5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Maturation of 5.8S rRNA →	+0.108	+1.086	<.001	.001	3	19
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.214	+1.418	<.001	<.001	3	19
LUNG_NSCLC_LUSC	rRNA 5'-end processing →	+0.175	+1.117	<.001	<.001	3	18
OESOPHAGUS	Maturation of SSU-rRNA →	+0.130	+0.811	<.001	.004	3	18
SOFT_TISSUE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.137	+0.977	<.001	<.001	3	18
LUNG_NSCLC_LUSC	Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.175	+1.117	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,353 associations by consensus.

Maturation of 5.8S rRNA by GEMIN5 expression — BLOOD_Myeloma

Explore this box plot interactively →