GEMIN4

Across TCGA cell cohorts, GEMIN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,385 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GEMIN4-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, XMP metabolic process, and XMP biosynthetic process. Each is linked with GEMIN4 in more than 19 cancer types. Because this analysis shows association rather than direction, both GEMIN4-to-partner and partner-to-GEMIN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by GEMIN4-low versus GEMIN4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN4→partner) and Y-score (partner→GEMIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	'de novo' IMP biosynthetic process →	+0.191	+1.097	<.001	<.001	3	20
LIVER	XMP metabolic process →	+0.163	+1.157	<.001	<.001	3	19
LIVER	XMP biosynthetic process →	+0.163	+1.157	<.001	<.001	3	19
LIVER	'de novo' XMP biosynthetic process →	+0.163	+1.157	<.001	<.001	3	19
PANCREAS	'de novo' AMP biosynthetic process →	+0.157	+1.014	<.001	<.001	3	18
URINARY_TRACT	Maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.126	+0.682	.001	.003	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,385 associations by consensus.

'de novo' IMP biosynthetic process by GEMIN4 expression — LIVER

Explore this box plot interactively →