GEMIN2P1

Across TCGA pan-cancer cohorts, GEMIN2P1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated GEMIN2P1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher GEMIN2P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GEMIN2P1 expression acts as an unfavorable survival marker, although some lineages such as LUSC and HNSC show a favorable association.

KICH, KIRP, and BRCA are the cancer types where GEMIN2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.372	0.922	<.001	72	view →
KIRP	DFS	Tertile	IV	0.088	0.502	<.001	54	view →
BRCA	DFS	Tertile	All	0.863	0.905	.036	48	view →
LUSC	DFS	Tertile	II,III,IV	0.957	0.682	.006	39	view →
LIHC	OS	Tertile	All	0.121	0.707	<.001	36	view →
UCEC	DFS	Tertile	All	0.821	0.909	.001	36	view →
THYM	OS	Tertile	All	0.186	0.931	.001	30	view →
HNSC	OS	Tertile	II,III,IV	1.000	0.351	.016	30	view →
KIRC	OS	Tertile	All	0.477	0.649	.010	27	view →
SKCM	OS	Tertile	II,III,IV	0.470	0.848	.005	21	view →
COAD	DFS	Tertile	III,IV	0.207	0.533	.041	18	view →
READ	OS	Tertile	IV	0.289	0.899	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

GEMIN2P1–KICH (DFS)

Open the KICH breakdown →