GEMIN2

Across TCGA cell cohorts, GEMIN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,821 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GEMIN2-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Methylation, and Monoubiquitinated protein deubiquitination. Each is linked with GEMIN2 in more than 14 cancer types. Because this analysis shows association rather than direction, both GEMIN2-to-partner and partner-to-GEMIN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by GEMIN2-low versus GEMIN2-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GEMIN2→partner) and Y-score (partner→GEMIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.186	+0.935	.004	.008	3	15
SKIN	Methylation →	+0.051	+0.801	<.001	.001	3	14
KIDNEY	Monoubiquitinated protein deubiquitination →	+0.105	+1.107	.002	<.001	3	14
SOFT_TISSUE	DNA-templated DNA replication →	+0.106	+1.121	<.001	<.001	3	14
LUNG_NSCLC_LUAD	DNA double-strand break processing →	+0.081	+1.061	<.001	<.001	3	13
BLOOD_Myeloma	Double-strand break repair →	+0.060	+1.122	.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,821 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by GEMIN2 expression — BLOOD_Myeloma

Explore this box plot interactively →