Across TCGA pan-cancer cohorts, GDPGP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GDPGP1 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher GDPGP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GDPGP1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where GDPGP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Tertile	All	0.895	0.616	.006	29	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	16	view →
LSCC	DFS	Tertile	All	0.871	1.000	.001	7	view →
HNSC	DFS	Quartile	IV	0.920	0.529	.030	5	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: GDPGP1 tumor-vs-normal RNA expression · all GDPGP1 data types