GDPD2

Across TCGA cell cohorts, GDPD2 mutation is significantly associated with the mutation status of many other genes, with 4,894 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GDPD2-associated genes across cancer lineages are CYTIP, SLC8A2, and PCDH17. Each is linked with GDPD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GDPD2-to-partner and partner-to-GDPD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYTIP grouped by GDPD2-low versus GDPD2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDPD2→partner) and Y-score (partner→GDPD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CYTIP →	+4.309	+4.560	.007	.007	1	3
BLOOD_Leukemia	SLC8A2 →	+4.157	+5.430	<.001	<.001	1	3
BLOOD_Leukemia	PCDH17 →	+2.572	+4.129	.009	.009	1	3
BLOOD_Leukemia	TEX14 →	+3.157	+4.665	.003	.003	1	3
BLOOD_Leukemia	ARFGEF2 →	+3.672	+5.083	.001	.001	1	3
SKIN	IRGC →	+4.824	+5.392	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,894 associations by consensus.

CYTIP by GDPD2 expression — BLOOD_Leukemia

Explore this box plot interactively →