GDPD1

Across TCGA patient cohorts, GDPD1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,012 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GDPD1-associated genes across cancer lineages are DNAJC27-AS1, MSI2, and STXBP4. Each is linked with GDPD1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GDPD1-to-partner and partner-to-GDPD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDPD1 versus DNAJC27-AS1 in GBM, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDPD1→partner) and Y-score (partner→GDPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DNAJC27-AS1 →	+0.594	+0.351	<.001	<.001	3	5
BRCA	MSI2 →	+0.882	+0.748	.001	<.001	3	5
LUAD	STXBP4 →	+0.534	+0.350	<.001	.001	3	5
BRCA	TRIM37 →	+0.572	+0.665	.002	.004	3	4
OV	COIL →	+0.556	+0.608	.001	.001	3	4
HNSC	DPH1 →	+0.432	+0.207	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,012 associations by consensus.

GDPD1 vs DNAJC27-AS1 — GBM

Explore this scatter interactively →