GDPD1

Across TCGA patient cohorts, GDPD1 mutation is significantly associated with the RNA expression of many other genes, with 566 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GDPD1-associated genes across cancer lineages are MIR4773-1, MIR4710, and MIR5691. Each is linked with GDPD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GDPD1-to-partner and partner-to-GDPD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4773-1 grouped by GDPD1-low versus GDPD1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDPD1→partner) and Y-score (partner→GDPD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR4773-1 →	+0.389	+4.038	<.001	.003	3	2
COAD	MIR4710 →	+0.713	+4.602	<.001	.008	3	2
STAD	MIR5691 →	+0.483	+4.090	<.001	.004	3	2
SKCM	SAPCD2P2 →	+0.025	+3.744	<.001	.003	3	2
BLCA	RNU6-1242P →	+0.328	+3.973	<.001	.003	3	2
UCEC	RNA5SP396 →	+0.344	+2.484	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 566 associations by consensus.

MIR4773-1 by GDPD1 expression — LUSC

Explore this box plot interactively →