GDI2

Across TCGA patient cohorts, GDI2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,402 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GDI2-associated proteins across cancer lineages are UPF2, LARP4B, and PFKP. Each is linked with GDI2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GDI2-to-partner and partner-to-GDI2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDI2 versus UPF2 in LSCC, with a Pearson correlation of 0.61.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GDI2→partner) and Y-score (partner→GDI2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UPF2 →	+0.258	+0.428	<.001	<.001	3	7
LSCC	LARP4B →	+0.298	+0.432	<.001	<.001	3	7
BRCA	PFKP →	+0.859	+0.648	<.001	<.001	3	6
BRCA	KIN →	+0.350	+0.419	<.001	<.001	3	6
HNSC	DNAJC2 →	+0.288	+0.779	<.001	.003	3	5
BRCA	HSPA14 →	+0.363	+0.486	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,402 associations by consensus.

GDI2 vs UPF2 — LSCC

Explore this scatter interactively →