Across TCGA patient cohorts, GDI1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,427 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GDI1-associated proteins across cancer lineages are SEC11C, MZB1, and TXNDC5. Each is linked with GDI1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GDI1-to-partner and partner-to-GDI1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GDI1→partner) and Y-score (partner→GDI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SEC11C →	-0.969	-0.328	<.001	<.001	3	5
GBM	MZB1 →	-0.863	-0.382	.002	.001	3	5
HNSC	TXNDC5 →	-0.514	-0.643	<.001	<.001	3	5
LUAD	EMD →	+0.445	+0.538	<.001	<.001	3	5
OV	FAM50A →	+0.323	+0.521	.001	.002	3	5
LSCC	SPCS3 →	-0.571	-0.429	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,427 associations by consensus.

Exploration

GDI1 survival (RNA) · tumor vs normal (RNA) · all GDI1 data types