Across TCGA patient cohorts, GDI1 mutation is significantly associated with the RNA expression of many other genes, with 4,769 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GDI1-associated genes across cancer lineages are RNU6-383P, LIM2, and CST8. Each is linked with GDI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GDI1-to-partner and partner-to-GDI1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDI1→partner) and Y-score (partner→GDI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNU6-383P →	+0.637	+5.329	<.001	.006	3	3
LGG	LIM2 →	+0.051	+4.223	.009	.009	3	2
LGG	CST8 →	+0.064	+4.679	<.001	.007	3	2
SKCM	KRTAP4-11 →	+0.783	+3.292	<.001	.006	3	2
SKCM	ZNF736P6Y →	+0.067	+3.970	<.001	.001	3	2
LGG	LINC01698 →	+0.048	+4.602	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,769 associations by consensus.

Exploration

GDI1 survival (RNA) · tumor vs normal (RNA) · all GDI1 data types