Across TCGA cell cohorts, GDI1 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GDI1-associated genes across cancer lineages are PHOX2B, IL2, and BTBD16. Each is linked with GDI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GDI1-to-partner and partner-to-GDI1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDI1→partner) and Y-score (partner→GDI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PHOX2B →	+0.025	+4.687	<.001	<.001	3	2
BLOOD_Leukemia	IL2 →	+0.657	+3.691	<.001	.002	3	1
BLOOD_Leukemia	BTBD16 →	+0.086	+3.959	<.001	.005	3	1
BLOOD_Leukemia	CD1B →	+3.544	+3.619	<.001	.007	3	1
BLOOD_Leukemia	TACR3 →	+0.025	+3.475	<.001	.006	3	1
BLOOD_Leukemia	SFT2D3 →	+0.521	+3.450	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

GDI1 survival (RNA) · tumor vs normal (RNA) · all GDI1 data types