GDF6

Across TCGA patient cohorts, GDF6 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,404 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GDF6-associated proteins across cancer lineages are FERMT2, VCAN, and CCDC80. Each is linked with GDF6 in more than 7 cancer types. Because this analysis shows association rather than direction, both GDF6-to-partner and partner-to-GDF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDF6 versus FERMT2 in BRCA, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF6→partner) and Y-score (partner→GDF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FERMT2 →	+0.843	+0.537	<.001	<.001	3	8
OV	VCAN →	+1.170	+0.754	<.001	<.001	3	7
OV	CCDC80 →	+1.020	+0.778	<.001	<.001	3	7
OV	FN1 →	+1.056	+0.609	<.001	<.001	3	7
COAD	ILK →	+0.446	+0.244	<.001	<.001	3	7
BRCA	KANK2 →	+0.748	+0.470	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,404 associations by consensus.

GDF6 vs FERMT2 — BRCA

Explore this scatter interactively →