Across TCGA cell cohorts, GDF5-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 556 significant associations in total. CNS shows the largest number of these associations.

The most reproducible GDF5-AS1-associated GO terms across cancer lineages are Neuropilin signaling pathway, Negative regulation of cell cycle G1/S phase transition, and Positive regulation of cyclin-dependent protein kinase activity. Each is linked with GDF5-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GDF5-AS1-to-partner and partner-to-GDF5-AS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF5-AS1→partner) and Y-score (partner→GDF5-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Neuropilin signaling pathway →	+0.092	+0.291	.001	.006	3	7
CNS	Negative regulation of cell cycle G1/S phase transition →	+0.050	+0.334	<.001	.007	2	6
CNS	Positive regulation of cyclin-dependent protein kinase activity →	+0.118	+0.600	<.001	<.001	3	5
CNS	Endocytic recycling →	+0.041	+0.403	.005	.001	3	5
CNS	Positive regulation of focal adhesion assembly →	+0.088	+0.371	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Negative regulation of cardiac muscle hypertrophy →	+0.085	+0.038	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 556 associations by consensus.

Exploration

GDF5-AS1 survival (RNA) · tumor vs normal (RNA) · all GDF5-AS1 data types