GDF5-AS1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GDF5-AS1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GDF5-AS1-associated genes across cancer lineages are UCMA and PRLH. Each is linked with GDF5-AS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GDF5-AS1-to-partner and partner-to-GDF5-AS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF5-AS1→partner) and Y-score (partner→GDF5-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKINUCMA →+0.046+4.977<.001.00731
SKINPRLH →+0.303+6.022<.001.00131
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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