Across TCGA patient cohorts, GDF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,127 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GDF3-associated GO terms across cancer lineages are Blood vessel endothelial cell migration, Branching involved in blood vessel morphogenesis, and Endothelium development. Each is linked with GDF3 in more than 23 cancer types. Because this analysis shows association rather than direction, both GDF3-to-partner and partner-to-GDF3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF3→partner) and Y-score (partner→GDF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Blood vessel endothelial cell migration →	+0.068	+0.151	.006	.003	3	24
STAD	Branching involved in blood vessel morphogenesis →	+0.070	+0.301	<.001	<.001	3	23
SCLC	Endothelium development →	+0.086	+0.179	<.001	.003	3	23
ESCA	Endothelial cell proliferation →	+0.067	+0.275	<.001	<.001	3	22
STAD	Blood vessel maturation →	+0.066	+0.292	<.001	<.001	3	22
STAD	Aorta morphogenesis →	+0.058	+0.302	<.001	<.001	3	22

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,127 associations by consensus.

Exploration

GDF3 survival (RNA) · tumor vs normal (RNA) · all GDF3 data types