GDF3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GDF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 292 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GDF3-associated GO terms across cancer lineages are Icosanoid catabolic process, Regulation of membrane tubulation, and Negative regulation of antigen processing and presentation of peptide antigen. Each is linked with GDF3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GDF3-to-partner and partner-to-GDF3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF3→partner) and Y-score (partner→GDF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaIcosanoid catabolic process →+0.220+0.355<.001.00732
BLOOD_LeukemiaRegulation of membrane tubulation →+0.131+0.355<.001.00732
BLOOD_LeukemiaNegative regulation of antigen processing and presentation of peptide antigen →-0.722-0.342<.001.00932
BLOOD_LeukemiaProtein-containing complex remodeling →+0.205+0.355<.001.00732
BLOOD_LeukemiaChylomicron remnant clearance →+1.067+0.229<.001.00232
BLOOD_LeukemiaXenobiotic transport →+0.093+0.351<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 292 associations by consensus.

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