GDF2

Across TCGA patient cohorts, GDF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 3,716 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GDF2-associated proteins across cancer lineages are USP16, BRF2_S353, and DYNLL2. Each is linked with GDF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GDF2-to-partner and partner-to-GDF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDF2 versus USP16 in GBM, with a Pearson correlation of -0.27.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF2→partner) and Y-score (partner→GDF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	USP16 →	-0.258	-0.073	<.001	.003	3	2
LUAD	BRF2_S353 →	+1.026	+0.013	<.001	.001	3	2
LSCC	DYNLL2 →	+0.266	+0.012	<.001	.002	3	2
LSCC	GORASP1 →	-0.182	-0.014	<.001	<.001	3	2
GBM	SDF2L1 →	-0.266	-0.046	<.001	.008	3	2
LUAD	SIPA1L1_S1170 →	-0.483	-0.014	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,716 associations by consensus.

GDF2 vs USP16 — GBM

Explore this scatter interactively →