GDF2

Across TCGA cell cohorts, GDF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 537 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GDF2-associated GO terms across cancer lineages are Oxygen transport, Modulation of excitatory postsynaptic potential, and Membrane repolarization during atrial cardiac muscle cell action potential. Each is linked with GDF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GDF2-to-partner and partner-to-GDF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oxygen transport grouped by GDF2-low versus GDF2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDF2→partner) and Y-score (partner→GDF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Oxygen transport →	+1.617	+0.450	<.001	.003	3	2
BLOOD_Leukemia	Modulation of excitatory postsynaptic potential →	-0.053	-0.199	<.001	.009	3	1
BLOOD_Leukemia	Membrane repolarization during atrial cardiac muscle cell action potential →	-1.092	-0.211	<.001	.005	3	1
BLOOD_Leukemia	Dendritic transport →	+0.081	+0.207	<.001	.007	3	1
BLOOD_Leukemia	Atrial cardiac muscle cell membrane repolarization →	-1.092	-0.211	<.001	.005	3	1
BLOOD_Leukemia	Sugar mediated signaling pathway →	-0.092	-0.254	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 537 associations by consensus.

Oxygen transport by GDF2 expression — BLOOD_Leukemia

Explore this box plot interactively →