Across TCGA patient cohorts, GDAP2 mutation is significantly associated with the RNA expression of many other genes, with 1,458 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GDAP2-associated genes across cancer lineages are MIR6803, CTLA4, and TYMS. Each is linked with GDAP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GDAP2-to-partner and partner-to-GDAP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDAP2→partner) and Y-score (partner→GDAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.105	+3.893	<.001	.006	3	3
UCEC	CTLA4 →	+0.755	+2.922	<.001	<.001	3	2
UCEC	TYMS →	+0.693	+2.329	.002	.003	3	2
UCEC	JMJD6 →	+0.494	+3.010	<.001	<.001	3	2
UCEC	TCF3 →	+0.488	+1.758	.001	.004	3	2
UCEC	WDR62 →	+0.623	+2.081	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,458 associations by consensus.

Exploration

GDAP2 survival (RNA) · tumor vs normal (RNA) · all GDAP2 data types