GDAP2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GDAP2 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GDAP2-associated genes across cancer lineages are mTOR_pS2448, eIF4E, and A-Raf_pS299. Each is linked with GDAP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GDAP2-to-partner and partner-to-GDAP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDAP2→partner) and Y-score (partner→GDAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECmTOR_pS2448 →-0.162-2.095.007.01733
UCECeIF4E →+0.191+3.459.024.00532
UCECA-Raf_pS299 →-0.149-2.000.001.03032
UCECMEK1 →+0.588+3.087<.001<.00132
UCECShc_pY317 →-0.210-1.906<.001.01632
UCECCaspase-7-cleavedD198 →+0.511+1.894.032.03032
Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration