GDA

Across TCGA patient cohorts, GDA RNA expression is significantly associated with the protein abundance of many other proteins, with 16,791 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GDA-associated proteins across cancer lineages are PLS1, PLEKHA1, and CAMSAP3. Each is linked with GDA in more than 4 cancer types. Because this analysis shows association rather than direction, both GDA-to-partner and partner-to-GDA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDA versus PLS1 in CCRCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GDA→partner) and Y-score (partner→GDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PLS1 →	+0.658	+1.772	<.001	<.001	3	5
GBM	PLEKHA1 →	+0.540	+1.259	<.001	<.001	3	5
GBM	CAMSAP3 →	+0.532	+1.299	<.001	<.001	3	5
GBM	CAMSAP3_S334 →	+0.632	+1.275	<.001	<.001	3	5
GBM	CAMSAP3_S554 →	+0.718	+1.262	<.001	<.001	3	5
LSCC	TACC2_S2512 →	+0.937	+1.578	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,791 associations by consensus.

GDA vs PLS1 — CCRCC

Explore this scatter interactively →