GDA

Across TCGA patient cohorts, GDA protein abundance is significantly associated with the RNA expression of many other genes, with 9,989 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GDA-associated genes across cancer lineages are CYP2C9, FUT3, and SOWAHB. Each is linked with GDA in more than 4 cancer types. Because this analysis shows association rather than direction, both GDA-to-partner and partner-to-GDA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDA versus CYP2C9 in LUAD, with a Pearson correlation of 0.64.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GDA→partner) and Y-score (partner→GDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CYP2C9 →	+1.883	+1.794	.004	<.001	3	5
LSCC	FUT3 →	+1.489	+0.987	<.001	.002	3	5
CCRCC	SOWAHB →	+0.951	+0.580	<.001	<.001	3	5
UCEC	VNN1 →	+2.471	+1.514	<.001	<.001	3	4
LUAD	TSPAN1 →	+1.947	+1.397	.001	.002	3	4
LUAD	LCN2 →	+2.190	+1.566	.005	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,989 associations by consensus.

GDA vs CYP2C9 — LUAD

Explore this scatter interactively →