GDA

Across TCGA patient cohorts, GDA protein abundance is significantly associated with the protein abundance of many other proteins, with 22,987 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GDA-associated proteins across cancer lineages are SLC9A3R1, SMARCA5, and SREK1. Each is linked with GDA in more than 5 cancer types. Because this analysis shows association rather than direction, both GDA-to-partner and partner-to-GDA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GDA versus SLC9A3R1 in LSCC, with a Pearson correlation of 0.54.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GDA→partner) and Y-score (partner→GDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SLC9A3R1 →	+0.620	+0.953	<.001	<.001	3	6
GBM	SMARCA5 →	-0.317	-0.618	<.001	.001	3	5
GBM	SREK1 →	-0.288	-0.680	<.001	<.001	3	5
UCEC	PRPF6 →	-0.281	-1.217	<.001	<.001	3	5
GBM	NUP160 →	-0.212	-0.636	<.001	<.001	3	5
LSCC	SLC9A3R1_S269 →	+0.772	+0.768	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,987 associations by consensus.

GDA vs SLC9A3R1 — LSCC

Explore this scatter interactively →