GDA

Across TCGA cell cohorts, GDA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,367 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible GDA-associated GO terms across cancer lineages are Purine deoxyribonucleoside metabolic process, Positive regulation of NK T cell proliferation, and Mammary gland duct morphogenesis. Each is linked with GDA in more than 10 cancer types. Because this analysis shows association rather than direction, both GDA-to-partner and partner-to-GDA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Purine deoxyribonucleoside metabolic process grouped by GDA-low versus GDA-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GDA→partner) and Y-score (partner→GDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Purine deoxyribonucleoside metabolic process →	-0.202	-1.318	<.001	.001	3	11
OVARY	Positive regulation of NK T cell proliferation →	+1.682	+3.177	<.001	<.001	3	8
BREAST	Mammary gland duct morphogenesis →	+0.195	+1.739	<.001	.001	3	8
BREAST	Purine deoxyribonucleoside catabolic process →	-0.302	-1.415	<.001	<.001	3	8
BREAST	Deoxyguanosine catabolic process →	-0.302	-1.415	<.001	<.001	3	8
STOMACH	Positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.175	+3.284	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,367 associations by consensus.

Purine deoxyribonucleoside metabolic process by GDA expression — BREAST

Explore this box plot interactively →