Across TCGA patient cohorts, GCSHP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,030 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GCSHP5-associated GO terms across cancer lineages are Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), Ribosome assembly, and Ribosomal large subunit biogenesis. Each is linked with GCSHP5 in more than 22 cancer types. Because this analysis shows association rather than direction, both GCSHP5-to-partner and partner-to-GCSHP5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCSHP5→partner) and Y-score (partner→GCSHP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.053	+0.302	<.001	<.001	3	23
UVM	Ribosome assembly →	+0.060	+0.345	<.001	<.001	3	22
ESCA	Ribosomal large subunit biogenesis →	+0.046	+0.381	<.001	<.001	3	22
UVM	Nuclear pore organization →	+0.085	+0.333	<.001	<.001	3	21
CHOL	Amino acid metabolic process →	+0.033	+0.359	.005	<.001	2	22
UVM	Maturation of SSU-rRNA →	+0.064	+0.343	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,030 associations by consensus.

Exploration

GCSHP5 survival (RNA) · tumor vs normal (RNA) · all GCSHP5 data types