GCSHP4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GCSHP4 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,417 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GCSHP4-associated proteins across cancer lineages are PLEC_S1581, PLEC_S1732, and NIBAN2_S681. Each is linked with GCSHP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both GCSHP4-to-partner and partner-to-GCSHP4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GCSHP4 versus PLEC_S1581 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GCSHP4→partner) and Y-score (partner→GCSHP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPLEC_S1581 →+0.631+0.251<.001<.00133
OVPLEC_S1732 →+0.631+0.251<.001<.00133
LSCCNIBAN2_S681 →-0.437-0.257.003.00633
LSCCCLASP2_S455 →+0.397+0.268<.001.00133
CCRCCUGDH_S476 →-1.018-0.382<.001<.00133
OVCHD2_S1688 →-0.743-0.213.002.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,417 associations by consensus.

GCSHP4 vs PLEC_S1581 — OV

Per-sample scatter of GCSHP4 vs PLEC_S1581 in OV (Pearson r = 0.37).

Explore this scatter interactively →

Exploration