GCSHP4

Across TCGA patient cohorts, GCSHP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,781 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GCSHP4-associated GO terms across cancer lineages are Positive regulation of leukocyte cell-cell adhesion, Antigen processing and presentation of exogenous peptide antigen, and Neutrophil chemotaxis. Each is linked with GCSHP4 in more than 20 cancer types. Because this analysis shows association rather than direction, both GCSHP4-to-partner and partner-to-GCSHP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of leukocyte cell-cell adhesion grouped by GCSHP4-low versus GCSHP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCSHP4→partner) and Y-score (partner→GCSHP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of leukocyte cell-cell adhesion →	+0.048	+0.114	<.001	<.001	3	21
ESCA	Antigen processing and presentation of exogenous peptide antigen →	+0.090	+0.207	<.001	<.001	3	20
LAML	Neutrophil chemotaxis →	+0.061	+0.508	<.001	<.001	3	20
DLBC	Gamma-delta T cell activation →	+0.077	+0.309	.002	.001	3	20
ESCA	Positive regulation of alpha-beta T cell activation →	+0.046	+0.148	<.001	.002	3	20
ESCA	Growth hormone receptor signaling pathway via JAK-STAT →	+0.097	+0.210	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,781 associations by consensus.

Positive regulation of leukocyte cell-cell adhesion by GCSHP4 expression — STAD

Explore this box plot interactively →