GCNT7

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, GCNT7 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GCNT7 data layer compared with 22 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher GCNT7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GCNT7 expression acts as an unfavorable survival marker.

PDAC, CCRCC, and GBM are the cancer types where GCNT7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PDACDFSTertileIII,IV0.2160.845.0249view →
CCRCCDFSMedianIV0.1501.000.0249view →
GBMDFSTertileAll0.6320.958.0208view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

GCNT7–PDAC (DFS)

Kaplan–Meier survival curve for GCNT7 mass-spec protein-high vs -low samples in PDAC.

Open the PDAC breakdown →

Exploration