GCNT7

Across TCGA patient cohorts, GCNT7 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GCNT7-associated genes across cancer lineages are Lck, EGFR_pY1068, and eIF4E. Each is linked with GCNT7 in more than 1 cancer types. Because this analysis shows association rather than direction, both GCNT7-to-partner and partner-to-GCNT7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lck grouped by GCNT7-low versus GCNT7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT7→partner) and Y-score (partner→GCNT7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Lck →	+0.317	+2.321	<.001	.034	3	2
UCEC	EGFR_pY1068 →	-0.323	-2.906	.002	.001	3	1
UCEC	eIF4E →	+0.235	+2.906	.008	.001	3	1
UCEC	ERK2 →	+0.311	+3.807	<.001	<.001	3	1
UCEC	Fibronectin →	-0.352	-3.156	.011	.018	3	1
UCEC	FOXO3a_pS318_S321 →	-0.144	-1.700	.006	.044	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Lck by GCNT7 expression — UCEC

Explore this box plot interactively →