GCNT4

Across TCGA cell cohorts, GCNT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,736 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GCNT4-associated GO terms across cancer lineages are Regulation of NMDA receptor activity, Ganglioside catabolic process, and Positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway. Each is linked with GCNT4 in more than 7 cancer types. Because this analysis shows association rather than direction, both GCNT4-to-partner and partner-to-GCNT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of NMDA receptor activity grouped by GCNT4-low versus GCNT4-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT4→partner) and Y-score (partner→GCNT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of NMDA receptor activity →	+1.724	+2.241	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Ganglioside catabolic process →	+0.159	+0.304	.002	.006	3	6
PANCREAS	Positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway →	+0.086	+0.678	.001	.001	3	6
OESOPHAGUS	Ureteric bud formation →	+1.564	+1.023	<.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Response to tumor necrosis factor →	+0.065	+0.779	.004	.007	3	6
URINARY_TRACT	White fat cell proliferation →	+1.200	+1.393	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,736 associations by consensus.

Regulation of NMDA receptor activity by GCNT4 expression — URINARY_TRACT

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