GCNT3

Across TCGA patient cohorts, GCNT3 mutation is significantly associated with the RNA expression of many other genes, with 2,025 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GCNT3-associated genes across cancer lineages are RNASEH2A, LRRC59, and CCND1. Each is linked with GCNT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GCNT3-to-partner and partner-to-GCNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASEH2A grouped by GCNT3-low versus GCNT3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT3→partner) and Y-score (partner→GCNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNASEH2A →	+0.616	+3.386	.004	.004	3	2
SKCM	LRRC59 →	+0.501	+3.208	.001	.009	3	2
SKCM	CCND1 →	+0.882	+3.478	.005	.002	3	2
SKCM	KIF20A →	+0.626	+2.719	.007	.003	3	2
SKCM	PFDN1 →	+0.389	+2.353	.002	.003	3	2
UCEC	PPP2CA →	+0.394	+2.960	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,025 associations by consensus.

RNASEH2A by GCNT3 expression — UCEC

Explore this box plot interactively →