GCNT3

Across TCGA cell cohorts, GCNT3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,060 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible GCNT3-associated GO terms across cancer lineages are GDF15-GFRAL signaling pathway, Intracellular sodium ion homeostasis, and Reduction of food intake in response to dietary excess. Each is linked with GCNT3 in more than 10 cancer types. Because this analysis shows association rather than direction, both GCNT3-to-partner and partner-to-GCNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GDF15-GFRAL signaling pathway grouped by GCNT3-low versus GCNT3-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT3→partner) and Y-score (partner→GCNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	GDF15-GFRAL signaling pathway →	+1.124	+1.468	<.001	.002	3	11
STOMACH	Intracellular sodium ion homeostasis →	+0.342	+3.312	<.001	<.001	3	9
LUNG_SCLC	Reduction of food intake in response to dietary excess →	+1.046	+0.996	<.001	.003	3	9
PANCREAS	Glial cell-derived neurotrophic factor receptor signaling pathway →	+0.820	+3.153	.006	<.001	3	8
LUNG_SCLC	Regulation of muscle adaptation →	+0.088	+1.706	<.001	.004	3	8
LUNG_SCLC	Monoacylglycerol metabolic process →	+0.163	+1.455	.004	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,060 associations by consensus.

GDF15-GFRAL signaling pathway by GCNT3 expression — LUNG_SCLC

Explore this box plot interactively →