GCNT3

Across TCGA cell cohorts, GCNT3 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GCNT3-associated genes across cancer lineages are IL3, SPAG11A, and RIPPLY1. Each is linked with GCNT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GCNT3-to-partner and partner-to-GCNT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL3 grouped by GCNT3-low versus GCNT3-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GCNT3→partner) and Y-score (partner→GCNT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	IL3 →	+0.020	+4.807	<.001	.006	3	1
BLOOD_Myeloma	SPAG11A →	+0.049	+4.807	<.001	.006	3	1
BLOOD_Lymphoma	RIPPLY1 →	+0.024	+4.191	.009	.007	3	1
BLOOD_Lymphoma	MBL2 →	+0.121	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	ANKRD33 →	+0.004	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	KRT3 →	+1.661	+4.350	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

IL3 by GCNT3 expression — BLOOD_Myeloma

Explore this box plot interactively →